| Records |
| Author |
Intrigila, Benedetto; Melatti, Igor; Tofani, Alberto; Macchiarelli, Guido |
| Title |
Computational models of myocardial endomysial collagen arrangement |
Type |
Journal Article |
| Year |
2007 |
Publication |
Computer Methods and Programs in Biomedicine |
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| Volume |
86 |
Issue  |
3 |
Pages |
232-244 |
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| Abstract |
Collagen extracellular matrix is one of the factors related to high passive stiffness of cardiac muscle. However, the architecture and the mechanical aspects of the cardiac collagen matrix are not completely known. In particular, endomysial collagen contribution to the passive mechanics of cardiac muscle as well as its micro anatomical arrangement is still a matter of debate. In order to investigate mechanical and structural properties of endomysial collagen, we consider two alternative computational models of some specific aspects of the cardiac muscle. These two models represent two different views of endomysial collagen distribution: (1) the traditional view and (2) a new view suggested by the data obtained from scanning electron microscopy (SEM) in NaOH macerated samples (a method for isolating collagen from the other tissue). We model the myocardial tissue as a net of spring elements representing the cardiomyocytes together with the endomysial collagen distribution. Each element is a viscous elastic spring, characterized by an elastic and a viscous constant. We connect these springs to imitate the interconnections between collagen fibers. Then we apply to the net of springs some external forces of suitable magnitude and direction, obtaining an extension of the net itself. In our setting, the ratio forces magnitude /net extension is intended to model the stress /strain ratio of a microscopical portion of the myocardial tissue. To solve the problem of the correct identification of the values of the different parameters involved, we use an artificial neural network approach. In particular, we use this technique to learn, given a distribution of external forces, the elastic constants of the springs needed to obtain a desired extension as an equilibrium position. Our experimental findings show that, in the model of collagen distribution structured according to the new view, a given stress /strain ratio (of the net of springs, in the sense specified above) is obtained with much smaller (w.r.t. the other model, corresponding to the traditional view) elasticity constants of the springs. This seems to indicate that by an appropriate structure, a given stiffness of the myocardial tissue can be obtained with endomysial collagen fibers of much smaller size. |
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Elsevier North-Holland, Inc. |
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New York, NY, USA |
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0169-2607 |
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yes |
| Call Number |
Sapienza @ mari @ Imtm07 |
Serial |
82 |
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| Author |
Hayes, B. P. ; Melatti, I.; Mancini, T.; Prodanovic, M.; Tronci, E. |
| Title |
Residential Demand Management using Individualised Demand Aware Price Policies |
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Journal Article |
| Year |
2017 |
Publication |
IEEE Transactions On Smart Grid |
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| Volume |
8 |
Issue |
3 |
Pages |
1284-1294 |
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MCLab @ davi @ |
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157 |
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| Author |
Cesta, Amedeo; Fratini, Simone; Orlandini, Andrea; Finzi, Alberto; Tronci, Enrico |
| Title |
Flexible Plan Verification: Feasibility Results |
Type |
Journal Article |
| Year |
2011 |
Publication |
Fundamenta Informaticae |
Abbreviated Journal |
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| Volume |
107 |
Issue |
2 |
Pages |
111-137 |
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yes |
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Sapienza @ mari @ fi11 |
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15 |
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| Author |
Intrigila, Benedetto; Salvo, Ivano; Sorgi, Stefano |
| Title |
A characterization of weakly Church-Rosser abstract reduction systems that are not Church-Rosser |
Type |
Journal Article |
| Year |
2001 |
Publication |
Information and Computation |
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| Volume |
171 |
Issue |
2 |
Pages |
137-155 |
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| Abstract |
Basic properties of rewriting systems can be stated in the framework of abstract reduction systems (ARS). Properties like confluence (or Church-Rosser, CR) and weak confluence (or weak Church-Rosser, WCR) and their relationships can be studied in this setting: as a matter of fact, well-known counterexamples to the implication WCR CR have been formulated as ARS. In this paper, starting from the observation that such counterexamples are structurally similar, we set out a graph-theoretic characterization of WCR ARS that is not CR in terms of a suitable class of reduction graphs, such that in every WCR not CR ARS, we can embed at least one element of this class. Moreover, we give a tighter characterization for a restricted class of ARS enjoying a suitable regularity condition. Finally, as a consequence of our approach, we prove some interesting results about ARS using the mathematical tools developed. In particular, we prove an extension of the Newman’s lemma and we find out conditions that, once assumed together with WCR property, ensure the unique normal form property. The Appendix treats two interesting examples, both generated by graph-rewriting rules, with specific combinatorial properties. |
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Academic Press, Inc. |
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Duluth, MN, USA |
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0890-5401 |
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yes |
| Call Number |
Sapienza @ mari @ Intrigila-Salvo-Sorgi:01 |
Serial |
68 |
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| Author |
Bono, V.; Salvo, I. |
| Title |
A CuCh Interpretation of an Object-Oriented Language |
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Journal Article |
| Year |
2001 |
Publication |
Electronic Notes in Theoretical Computer Science |
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| Volume |
50 |
Issue |
2 |
Pages |
159-177 |
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CuCh machine extends pure lambda–calculus with algebraic data types and provides a the possibility of defining functions over the disjoint sum of algebras. We exploit such natural form of overloading to define a functional interpretation of a simple, but significant fragment of a typical object-oriented language. |
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Elsevier |
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BOTH 2001, Bohm’s theorem: applications to Computer Science Theory (Satellite Workshop of ICALP 2001) |
Approved |
yes |
| Call Number |
Sapienza @ mari @ Bono-Salvo:BOTH01 |
Serial |
72 |
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| Author |
Alimguzhin, V.; Mari, F.; Melatti, I.; Salvo, I.; Tronci, E. |
| Title |
Linearising Discrete Time Hybrid Systems |
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Journal Article |
| Year |
2017 |
Publication |
IEEE Transactions on Automatic Control |
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62 |
Issue |
10 |
Pages |
5357-5364 |
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Model Based Design approaches for embedded systems aim at generating correct-by-construction control software, guaranteeing that the closed loop system (controller and plant) meets given system level formal specifications. This technical note addresses control synthesis for safety and reachability properties of possibly non-linear discrete time hybrid systems. By means of syntactical transformations that require non-linear terms to be Lipschitz continuous functions, we over-approximate non-linear dynamics with a linear system whose controllers are guaranteed to be controllers of the original system. We evaluate performance of our approach on meaningful control synthesis benchmarks, also comparing it to a state-of-the-art tool. |
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0018-9286 |
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no |
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Sapienza @ mari @ ref7902199 |
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164 |
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| Author |
Mancini, T. |
| Title |
Now or Never: Negotiating Efficiently with Unknown or Untrusted Counterparts |
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Journal Article |
| Year |
2016 |
Publication |
Fundamenta Informaticae |
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149 |
Issue |
1-2 |
Pages |
61-100 |
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MCLab @ davi @ DBLP:journals/fuin/Mancini16 |
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161 |
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| Author |
Mancini, T.; Mari, F.; Massini, A.; Melatti, I.; Tronci, E. |
| Title |
SyLVaaS: System Level Formal Verification as a Service |
Type |
Journal Article |
| Year |
2016 |
Publication |
Fundamenta Informaticae |
Abbreviated Journal |
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| Volume |
149 |
Issue |
1-2 |
Pages |
101-132 |
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MCLab @ davi @ DBLP:journals/fuin/ManciniMMMT16 |
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160 |
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Tronci, Enrico |
| Title |
Equational Programming in Lambda-Calculus via SL-Systems. Part 1 |
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Journal Article |
| Year |
1996 |
Publication |
Theoretical Computer Science |
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160 |
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1&2 |
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145-184 |
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yes |
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Sapienza @ mari @ tcs96 |
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54 |
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| Author |
Tronci, Enrico |
| Title |
Equational Programming in Lambda-Calculus via SL-Systems. Part 2 |
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Journal Article |
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1996 |
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Theoretical Computer Science |
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160 |
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1&2 |
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185-216 |
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yes |
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Sapienza @ mari @ tcs96a |
Serial |
55 |
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