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	Author	Gribaudo, Marco; HorvÃ¡th, Andras; Bobbio, Andrea; Tronci, Enrico; Ciancamerla, Ester; Minichino, Michele
	Title	Fluid Petri Nets and hybrid model checking: a comparative case study			Type	Journal Article
	Year	2003	Publication	Int. Journal on: Reliability Engineering & System Safety	Abbreviated Journal
	Volume	81	Issue	3	Pages	239-257
	Keywords
	Abstract	The modeling and analysis of hybrid systems is a recent and challenging research area which is actually dominated by two main lines: a functional analysis based on the description of the system in terms of discrete state (hybrid) automata (whose goal is to ascertain conformity and reachability properties), and a stochastic analysis (whose aim is to provide performance and dependability measures). This paper investigates a unifying view between formal methods and stochastic methods by proposing an analysis methodology of hybrid systems based on Fluid Petri Nets (FPNs). FPNs can be analyzed directly using appropriate tools. Our paper shows that the same FPN model can be fed to different functional analyzers for model checking. In order to extensively explore the capability of the technique, we have converted the original FPN into languages for discrete as well as hybrid as well as stochastic model checkers. In this way, a first comparison among the modeling power of well known tools can be carried out. Our approach is illustrated by means of a Ã¢â‚¬â„¢real worldÃ¢â‚¬â„¢ hybrid system: the temperature control system of a co-generative plant.
	Address
	Corporate Author				Thesis
	Publisher	Elsevier	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ ress03			Serial	40
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	Author	Focardi, Riccardo; Gorrieri, Roberto; Lanotte, Ruggero; Maggiolo-Schettini, Andrea; Martinelli, Fabio; Tini, Simone; Tronci, Enrico
	Title	Formal Models of Timing Attacks on Web Privacy			Type	Journal Article
	Year	2002	Publication	Electronic Notes in Theoretical Computer Science	Abbreviated Journal
	Volume	62	Issue		Pages	229-243
	Keywords
	Abstract	We model a timing attack on web privacy proposed by Felten and Schneider by using three different approaches: HL-Timed Automata, SMV model checker, and tSPA Process Algebra. Some comparative analysis on the three approaches is derived.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes	TOSCA 2001, Theory of Concurrency, Higher Order Languages and Types			Approved	yes
	Call Number	Sapienza @ mari @ entcs02a			Serial	47
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	Author	Cesta, Amedeo; Finzi, Alberto; Fratini, Simone; Orlandini, Andrea; Tronci, Enrico
	Title	Validation and verification issues in a timeline-based planning system			Type	Journal Article
	Year	2010	Publication	The Knowledge Engineering Review	Abbreviated Journal
	Volume	25	Issue	03	Pages	299-318
	Keywords
	Abstract	One of the key points to take into account to foster effective introduction of AI planning and scheduling systems in real world is to develop end user trust in the related technologies. Automated planning and scheduling systems often brings solutions to the users which are neither Ã¢â‚¬Å“obviousÃ¢â‚¬Â nor immediately acceptable for them. This is due to the ability of these tools to take into account quite an amount of temporal and causal constraints and to employ resolution processes often designed to optimize the solution with respect to non trivial evaluation functions. To increase technology trust, the study of tools for verifying and validating plans and schedules produced by AI systems might be instrumental. In general, validation and verification techniques represent a needed complementary technology in developing domain independent architectures for automated problem solving. This paper presents a preliminary report of the issues concerned with the use of two software tools for formal verification of finite state systems to the validation of the solutions produced by MrSPOCK, a recent effort for building a timeline based planning tool in an ESA project.
	Address
	Corporate Author				Thesis
	Publisher	Cambridge University Press	Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ Cffot10			Serial	18
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	Author	Tronci, Enrico
	Title	Defining Data Structures via BÃ¶hm-Out			Type	Journal Article
	Year	1995	Publication	J. Funct. Program.	Abbreviated Journal
	Volume	5	Issue	1	Pages	51-64
	Keywords
	Abstract	We show that any recursively enumerable subset of a data structure can be regarded as the solution set to a B??hm-out problem.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ jfp95			Serial	57
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	Author	Sinisi, S.; Alimguzhin, V.; Mancini, T.; Tronci, E.; Leeners, B.
	Title	Complete populations of virtual patients for in silico clinical trials			Type	Journal Article
	Year	2021	Publication	Bioinformatics	Abbreviated Journal
	Volume		Issue		Pages	1-8
	Keywords
	Abstract	Model-based approaches to safety and efficacy assessment of pharmacological drugs, treatment strategies, or medical devices (In Silico Clinical Trial, ISCT) aim to decrease time and cost for the needed experimentations, reduce animal and human testing, and enable precision medicine. Unfortunately, in presence of non-identifiable models (e.g., reaction networks), parameter estimation is not enough to generate complete populations of Virtual Patient (VPs), i.e., populations guaranteed to show the entire spectrum of model behaviours (phenotypes), thus ensuring representativeness of the trial.We present methods and software based on global search driven by statistical model checking that, starting from a (non-identifiable) quantitative model of the human physiology (plus drugs PK/PD) and suitable biological and medical knowledge elicited from experts, compute a population of VPs whose behaviours are representative of the whole spectrum of phenotypes entailed by the model (completeness) and pairwise distinguishable according to user-provided criteria. This enables full granularity control on the size of the population to employ in an ISCT, guaranteeing representativeness while avoiding over-representation of behaviours.We proved the effectiveness of our algorithm on a non-identifiable ODE-based model of the female Hypothalamic-Pituitary-Gonadal axis, by generating a population of 4 830 264 VPs stratified into 7 levels (at different granularity of behaviours), and assessed its representativeness against 86 retrospective health records from Pfizer, Hannover Medical School and University Hospital of Lausanne. The datasets are respectively covered by our VPs within Average Normalised Mean Absolute Error of 15%, 20%, and 35% (90% of the latter dataset is covered within 20% error).
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1367-4803	ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	no
	Call Number	MCLab @ davi @ ref10.1093/bioinformatics/btaa1026			Serial	182
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	Author	Maggioli, F.; Mancini, T.; Tronci, E.
	Title	SBML2Modelica: Integrating biochemical models within open-standard simulation ecosystems			Type	Journal Article
	Year	2019	Publication	Bioinformatics	Abbreviated Journal
	Volume	36	Issue	7	Pages	2165â€“2172
	Keywords
	Abstract	SBML is the most widespread language for the definition of biochemical models. Although dozens of SBML simulators are available, there is a general lack of support to the integration of SBML models within open-standard general-purpose simulation ecosystems. This hinders co-simulation and integration of SBML models within larger model networks, in order to, e.g., enable in-silico clinical trials of drugs, pharmacological protocols, or engineering artefacts such as biomedical devices against Virtual Physiological Human models.Modelica is one of the most popular existing open-standard general-purpose simulation languages, supported by many simulators. Modelica models are especially suited for the definition of complex networks of heterogeneous models from virtually all application domains. Models written in Modelica (and in 100+ other languages) can be readily exported into black-box Functional Mock-Up Units (FMUs), and seamlessly co-simulated and integrated into larger model networks within open-standard language-independent simulation ecosystems.In order to enable SBML model integration within heterogeneous model networks, we present SBML2Modelica, a software system translating SBML models into well-structured, user-intelligible, easily modifiable Modelica models. SBML2Modelica is SBML Level 3 Version 2 -compliant and succeeds on 96.47% of the SBML Test Suite Core (with a few rare, intricate, and easily avoidable combinations of constructs unsupported and cleanly signalled to the user). Our experimental campaign on 613 models from the BioModels database (with up to 5438 variables) shows that the major open-source (general-purpose) Modelica and FMU simulators achieve performance comparable to state-of-the-art specialised SBML simulators.SBML2Modelica is written in Java and is freely available for non-commercial use at https://bitbucket.org/mclab/sbml2modelica
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1367-4803	ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	no
	Call Number	MCLab @ davi @ ref10.1093/bioinformatics/btz860			Serial	179
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	Author	Tronci, Enrico; Della Penna, Giuseppe; Intrigila, Benedetto; Venturini Zilli, Marisa
	Title	A Probabilistic Approach to Automatic Verification of Concurrent Systems			Type	Conference Article
	Year	2001	Publication	8th Asia-Pacific Software Engineering Conference (APSEC)	Abbreviated Journal
	Volume		Issue		Pages	317-324
	Keywords
	Abstract	The main barrier to automatic verification of concurrent systems is the huge amount of memory required to complete the verification task (state explosion). In this paper we present a probabilistic algorithm for automatic verification via model checking. Our algorithm trades space with time. In particular, when memory is full because of state explosion our algorithm does not give up verification. Instead it just proceeds at a lower speed and its results will only hold with some arbitrarily small error probability. Our preliminary experimental results show that by using our probabilistic algorithm we can typically save more than 30% of RAM with an average time penalty of about 100% w.r.t. a deterministic state space exploration with enough memory to complete the verification task. This is better than giving up the verification task because of lack of memory.
	Address
	Corporate Author				Thesis
	Publisher	IEEE Computer Society	Place of Publication	Macau, China	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0-7695-1408-1	ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ apsec01			Serial	43
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	Author	Brizzolari, Francesco; Melatti, Igor; Tronci, Enrico; Della Penna, Giuseppe
	Title	Disk Based Software Verification via Bounded Model Checking			Type	Conference Article
	Year	2007	Publication	APSEC '07: Proceedings of the 14th Asia-Pacific Software Engineering Conference	Abbreviated Journal
	Volume		Issue		Pages	358-365
	Keywords
	Abstract	One of the most successful approach to automatic software verification is SAT based bounded model checking (BMC). One of the main factors limiting the size of programs that can be automatically verified via BMC is the huge number of clauses that the backend SAT solver has to process. In fact, because of this, the SAT solver may easily run out of RAM. We present two disk based algorithms that can considerably decrease the number of clauses that a BMC backend SAT solver has to process in RAM. Our experimental results show that using our disk based algorithms we can automatically verify programs that are out of reach for RAM based BMC.
	Address
	Corporate Author				Thesis
	Publisher	IEEE Computer Society	Place of Publication	Washington, DC, USA	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0-7695-3057-5	ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ Bmtd07			Serial	76
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	Author	Tronci, Enrico
	Title	Automatic Synthesis of Control Software for an Industrial Automation Control System			Type	Conference Article
	Year	1999	Publication	Proc.of: 14th IEEE International Conference on: Automated Software Engineering (ASE)	Abbreviated Journal
	Volume		Issue		Pages	247-250
	Keywords
	Abstract	We present a case study on automatic synthesis of control software from formal specifications for an industrial automation control system. Our aim is to compare the effectiveness (i.e. design effort and controller quality) of automatic controller synthesis from closed loop formal specifications with that of manual controller design, followed by automatic verification. Our experimental results show that for industrial automation control systems, automatic synthesis is a viable and profitable (especially as far as design effort is concerned) alternative to manual design, followed by automatic verification.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication	Cocoa Beach, Florida, USA	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ ase99			Serial	49
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	Author	Tronci, Enrico
	Title	Optimal Finite State Supervisory Control			Type	Conference Article
	Year	1996	Publication	CDC '96: Proceedings of the 35th IEEE International Conference on Decision and Control	Abbreviated Journal
	Volume		Issue		Pages
	Keywords
	Abstract	Supervisory Controllers are Discrete Event Dynamic Systems (DEDSs) forming the discrete core of a Hybrid Control System. We address the problem of automatic synthesis of Optimal Finite State Supervisory Controllers (OSCs). We show that Boolean First Order Logic (BFOL) and Binary Decision Diagrams (BDDs) are an effective methodological and practical framework for Optimal Finite State Supervisory Control. Using BFOL programs (i.e. systems of boolean functional equations) and BDDs we give a symbolic (i.e. BDD based) algorithm for automatic synthesis of OSCs. Our OSC synthesis algorithm can handle arbitrary sets of final states as well as plant transition relations containing loops and uncontrollable events (e.g. failures). We report on experimental results on the use of our OSC synthesis algorithm to synthesize a C program implementing a minimum fuel OSC for two autonomous vehicles moving on a 4 x 4 grid.
	Address
	Corporate Author				Thesis
	Publisher	IEEE Computer Society	Place of Publication	Washington, DC, USA	Editor
	Language		Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN		ISBN		Medium
	Area		Expedition		Conference
	Notes				Approved	yes
	Call Number	Sapienza @ mari @ cdc96			Serial	67
Permanent link to this record