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Verzino Giovanni, Federico Cavaliere, Federico Mari, Igor Melatti, Giovanni Minei, Ivano Salvo, Yuri Yushtein, and Enrico Tronci. "Model checking driven simulation of sat procedures." In Proceedings of 12th International Conference on Space Operations (SpaceOps 2012)., 2012. DOI: 10.2514/6.2012-1275611.
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Enrico Tronci, Giuseppe Della Penna, Benedetto Intrigila, and Marisa Venturini Zilli. "Exploiting Transition Locality in Automatic Verification." In 11th IFIP WG 10.5 Advanced Research Working Conference on Correct Hardware Design and Verification Methods (CHARME), edited by T. Margaria and T. F. Melham, 259–274. Lecture Notes in Computer Science 2144. Livingston, Scotland, UK: Springer, 2001. ISSN: 3-540-42541-1. DOI: 10.1007/3-540-44798-9_22.
Abstract: In this paper we present an algorithm to contrast state explosion when using Explicit State Space Exploration to verify protocols. We show experimentally that protocols exhibit transition locality. We present a verification algorithm that exploits transition locality as well as an implementation of it within the Mur$\varphi$ verifier. Our algorithm is compatible with all Breadth First (BF) optimization techniques present in the Mur$\varphi$ verifier and it is by no means a substitute for any of them. In fact, since our algorithm trades space with time, it is typically most useful when one runs out of memory and has already used all other state reduction techniques present in the Mur$\varphi$ verifier. Our experimental results show that using our approach we can typically save more than 40% of RAM with an average time penalty of about 50% when using (Mur$\varphi$) bit compression and 100% when using bit compression and hash compaction.
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Enrico Tronci, Giuseppe Della Penna, Benedetto Intrigila, and Marisa Venturini Zilli. "A Probabilistic Approach to Automatic Verification of Concurrent Systems." In 8th Asia-Pacific Software Engineering Conference (APSEC), 317–324. Macau, China: IEEE Computer Society, 2001. ISSN: 0-7695-1408-1. DOI: 10.1109/APSEC.2001.991495.
Abstract: The main barrier to automatic verification of concurrent systems is the huge amount of memory required to complete the verification task (state explosion). In this paper we present a probabilistic algorithm for automatic verification via model checking. Our algorithm trades space with time. In particular, when memory is full because of state explosion our algorithm does not give up verification. Instead it just proceeds at a lower speed and its results will only hold with some arbitrarily small error probability. Our preliminary experimental results show that by using our probabilistic algorithm we can typically save more than 30% of RAM with an average time penalty of about 100% w.r.t. a deterministic state space exploration with enough memory to complete the verification task. This is better than giving up the verification task because of lack of memory.
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E. Tronci, T. Mancini, I. Salvo, F. Mari, I. Melatti, A. Massini, S. Sinisi, F. Davì, T. Dierkes, R. Ehrig et al. "Patient-Specific Models from Inter-Patient Biological Models and Clinical Records." In Formal Methods in Computer-Aided Design (FMCAD)., 2014. DOI: 10.1109/FMCAD.2014.6987615.
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E. Tronci, T. Mancini, F. Mari, I. Melatti, I. Salvo, M. Prodanovic, J. K. Gruber, B. Hayes, and L. Elmegaard. "Demand-Aware Price Policy Synthesis and Verification Services for Smart Grids." In Proceedings of Smart Grid Communications (SmartGridComm), 2014 IEEE International Conference On., 2014. DOI: 10.1109/SmartGridComm.2014.7007745.
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E. Tronci, T. Mancini, F. Mari, I. Melatti, R. H. Jacobsen, E. Ebeid, S. A. Mikkelsen, M. Prodanovic, J. K. Gruber, and B. Hayes. "SmartHG: Energy Demand Aware Open Services for Smart Grid Intelligent Automation." In Proceedings of the Work in Progress Session of SEAA/DSD 2014., 2014. ISBN: 978-3-902457-40-0.
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Toni Mancini, Enrico Tronci, Ivano Salvo, Federico Mari, Annalisa Massini, and Igor Melatti. "Computing Biological Model Parameters by Parallel Statistical Model Checking." International Work Conference on Bioinformatics and Biomedical Engineering (IWBBIO 2015) 9044 (2015): 542–554. DOI: 10.1007/978-3-319-16480-9_52.
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S. Sinisi, V. Alimguzhin, T. Mancini, E. Tronci, F. Mari, and B. Leeners. "Optimal Personalised Treatment Computation through In Silico Clinical Trials on Patient Digital Twins." Fundamenta Informaticae 174 (2020): 283–310. IOS Press. ISSN: 1875-8681. DOI: 10.3233/FI-2020-1943.
Abstract: In Silico Clinical Trials (ISCT), i.e. clinical experimental campaigns carried out by means of computer simulations, hold the promise to decrease time and cost for the safety and efficacy assessment of pharmacological treatments, reduce the need for animal and human testing, and enable precision medicine. In this paper we present methods and an algorithm that, by means of extensive computer simulation-based experimental campaigns (ISCT) guided by intelligent search, optimise a pharmacological treatment for an individual patient (precision medicine ). We show the effectiveness of our approach on a case study involving a real pharmacological treatment, namely the downregulation phase of a complex clinical protocol for assisted reproduction in humans.
Keywords: Artificial Intelligence; Virtual Physiological Human; In Silico Clinical Trials; Simulation; Personalised Medicine; In Silico Treatment Optimisation
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I. Melatti, F. Mari, T. Mancini, M. Prodanovic, and E. Tronci. "A Two-Layer Near-Optimal Strategy for Substation Constraint Management via Home Batteries." IEEE Transactions on Industrial Electronics (2021): 1. Notes: To appear. DOI: 10.1109/TIE.2021.3102431.
Abstract: Within electrical distribution networks, substation constraints management requires that aggregated power demand from residential users is kept within suitable bounds. Efficiency of substation constraints management can be measured as the reduction of constraints violations w.r.t. unmanaged demand. Home batteries hold the promise of enabling efficient and user-oblivious substation constraints management. Centralized control of home batteries would achieve optimal efficiency. However, it is hardly acceptable by users, since service providers (e.g., utilities or aggregators) would directly control batteries at user premises. Unfortunately, devising efficient hierarchical control strategies, thus overcoming the above problem, is far from easy. We present a novel two-layer control strategy for home batteries that avoids direct control of home devices by the service provider and at the same time yields near-optimal substation constraints management efficiency. Our simulation results on field data from 62 households in Denmark show that the substation constraints management efficiency achieved with our approach is at least 82% of the one obtained with a theoretical optimal centralized strategy.
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Silvia Mazzini, Stefano Puri, Federico Mari, Igor Melatti, and Enrico Tronci. "Formal Verification at System Level." In In: DAta Systems In Aerospace (DASIA), Org. EuroSpace, Canadian Space Agency, CNES, ESA, EUMETSAT. Instanbul, Turkey, EuroSpace., 2009.
Abstract: System Level Analysis calls for a language comprehensible to experts with different background and yet precise enough to support meaningful analyses. SysML is emerging as an effective balance between such conflicting goals. In this paper we outline some the results obtained as for SysML based system level functional formal verification by an ESA/ESTEC study, with a collaboration among INTECS and La Sapienza University of Roma. The study focuses on SysML based system level functional requirements techniques.
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