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Giuseppe Della Penna, Benedetto Intrigila, Igor Melatti, Enrico Tronci, and Marisa Venturini Zilli. "Finite Horizon Analysis of Markov Chains with the Mur$\varphi$ Verifier." In Correct Hardware Design and Verification Methods, 12th IFIP WG 10.5 Advanced Research Working Conference, CHARME 2003, L'Aquila, Italy, October 21-24, 2003, Proceedings, edited by D. Geist and E. Tronci, 394–409. Lecture Notes in Computer Science 2860. Springer, 2003. ISSN: 3-540-20363-X. DOI: 10.1007/978-3-540-39724-3_34.
Abstract: In this paper we present an explicit disk based verification algorithm for Probabilistic Systems defining discrete time/finite state Markov Chains. Given a Markov Chain and an integer k (horizon), our algorithm checks whether the probability of reaching an error state in at most k steps is below a given threshold. We present an implementation of our algorithm within a suitable extension of the Mur$\varphi$ verifier. We call the resulting probabilistic model checker FHP-Mur$\varphi$ (Finite Horizon Probabilistic Mur$\varphi$). We present experimental results comparing FHP-Mur$\varphi$ with (a finite horizon subset of) PRISM, a state-of-the-art symbolic model checker for Markov Chains. Our experimental results show that FHP-Mur$\varphi$ can handle systems that are out of reach for PRISM, namely those involving arithmetic operations on the state variables (e.g. hybrid systems).
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Giuseppe Della Penna, Benedetto Intrigila, Igor Melatti, Enrico Tronci, and Marisa Venturini Zilli. "Exploiting Transition Locality in Automatic Verification of Finite State Concurrent Systems." Sttt 6, no. 4 (2004): 320–341. DOI: 10.1007/s10009-004-0149-6.
Abstract: In this paper we show that statistical properties of the transition graph of a system to be verified can be exploited to improve memory or time performances of verification algorithms. We show experimentally that protocols exhibit transition locality. That is, with respect to levels of a breadth-first state space exploration, state transitions tend to be between states belonging to close levels of the transition graph. We support our claim by measuring transition locality for the set of protocols included in the Mur$\varphi$ verifier distribution. We present a cache-based verification algorithm that exploits transition locality to decrease memory usage and a disk-based verification algorithm that exploits transition locality to decrease disk read accesses, thus reducing the time overhead due to disk usage. Both algorithms have been implemented within the Mur$\varphi$ verifier. Our experimental results show that our cache-based algorithm can typically save more than 40% of memory with an average time penalty of about 50% when using (Mur$\varphi$) bit compression and 100% when using bit compression and hash compaction, whereas our disk-based verification algorithm is typically more than ten times faster than a previously proposed disk-based verification algorithm and, even when using 10% of the memory needed to complete verification, it is only between 40 and 530% (300% on average) slower than (RAM) Mur$\varphi$ with enough memory to complete the verification task at hand. Using just 300 MB of memory our disk-based Mur$\varphi$ was able to complete verification of a protocol with about $10^9$ reachable states. This would require more than 5 GB of memory using standard Mur$\varphi$.
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Enrico Tronci, Giuseppe Della Penna, Benedetto Intrigila, and Marisa Venturini Zilli. "A Probabilistic Approach to Automatic Verification of Concurrent Systems." In 8th Asia-Pacific Software Engineering Conference (APSEC), 317–324. Macau, China: IEEE Computer Society, 2001. ISSN: 0-7695-1408-1. DOI: 10.1109/APSEC.2001.991495.
Abstract: The main barrier to automatic verification of concurrent systems is the huge amount of memory required to complete the verification task (state explosion). In this paper we present a probabilistic algorithm for automatic verification via model checking. Our algorithm trades space with time. In particular, when memory is full because of state explosion our algorithm does not give up verification. Instead it just proceeds at a lower speed and its results will only hold with some arbitrarily small error probability. Our preliminary experimental results show that by using our probabilistic algorithm we can typically save more than 30% of RAM with an average time penalty of about 100% w.r.t. a deterministic state space exploration with enough memory to complete the verification task. This is better than giving up the verification task because of lack of memory.
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T. Mancini, F. Mari, I. Melatti, I. Salvo, and E. Tronci. "An Efficient Algorithm for Network Vulnerability Analysis Under Malicious Attacks." In Foundations of Intelligent Systems – 24th International Symposium, ISMIS 2018, Limassol, Cyprus, October 29-31, 2018, Proceedings, 302–312., 2018. Notes: Best Paper. DOI: 10.1007/978-3-030-01851-1_29.
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Toni Mancini, Federico Mari, Annalisa Massini, Igor Melatti, Fabio Merli, and Enrico Tronci. "System Level Formal Verification via Model Checking Driven Simulation." In Proceedings of the 25th International Conference on Computer Aided Verification. July 13-19, 2013, Saint Petersburg, Russia, 296–312. Lecture Notes in Computer Science 8044. Springer - Verlag, 2013. ISSN: 0302-9743. ISBN: 978-3-642-39798-1. DOI: 10.1007/978-3-642-39799-8_21.
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S. Sinisi, V. Alimguzhin, T. Mancini, E. Tronci, F. Mari, and B. Leeners. "Optimal Personalised Treatment Computation through In Silico Clinical Trials on Patient Digital Twins." Fundamenta Informaticae 174 (2020): 283–310. IOS Press. ISSN: 1875-8681. DOI: 10.3233/FI-2020-1943.
Abstract: In Silico Clinical Trials (ISCT), i.e. clinical experimental campaigns carried out by means of computer simulations, hold the promise to decrease time and cost for the safety and efficacy assessment of pharmacological treatments, reduce the need for animal and human testing, and enable precision medicine. In this paper we present methods and an algorithm that, by means of extensive computer simulation-based experimental campaigns (ISCT) guided by intelligent search, optimise a pharmacological treatment for an individual patient (precision medicine ). We show the effectiveness of our approach on a case study involving a real pharmacological treatment, namely the downregulation phase of a complex clinical protocol for assisted reproduction in humans.
Keywords: Artificial Intelligence; Virtual Physiological Human; In Silico Clinical Trials; Simulation; Personalised Medicine; In Silico Treatment Optimisation
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Giuseppe Della Penna, Benedetto Intrigila, Igor Melatti, Enrico Tronci, and Marisa Venturini Zilli. "Integrating RAM and Disk Based Verification within the Mur$\varphi$ Verifier." In Correct Hardware Design and Verification Methods, 12th IFIP WG 10.5 Advanced Research Working Conference, CHARME 2003, L'Aquila, Italy, October 21-24, 2003, Proceedings, edited by D. Geist and E. Tronci, 277–282. Lecture Notes in Computer Science 2860. Springer, 2003. ISSN: 3-540-20363-X. DOI: 10.1007/978-3-540-39724-3_25.
Abstract: We present a verification algorithm that can automatically switch from RAM based verification to disk based verification without discarding the work done during the RAM based verification phase. This avoids having to choose beforehand the proper verification algorithm. Our experimental results show that typically our integrated algorithm is as fast as (sometime faster than) the fastest of the two base (i.e. RAM based and disk based) verification algorithms.
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Federico Mari, Igor Melatti, Enrico Tronci, and Alberto Finzi. "A multi-hop advertising discovery and delivering protocol for multi administrative domain MANET." Mobile Information Systems 3, no. 9 (2013): 261–280. IOS Press. ISSN: 1574-017x (Print) 1875-905X (Online). DOI: 10.3233/MIS-130162.
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Enrico Tronci, Giuseppe Della Penna, Benedetto Intrigila, and Marisa Venturini Zilli. "Exploiting Transition Locality in Automatic Verification." In 11th IFIP WG 10.5 Advanced Research Working Conference on Correct Hardware Design and Verification Methods (CHARME), edited by T. Margaria and T. F. Melham, 259–274. Lecture Notes in Computer Science 2144. Livingston, Scotland, UK: Springer, 2001. ISSN: 3-540-42541-1. DOI: 10.1007/3-540-44798-9_22.
Abstract: In this paper we present an algorithm to contrast state explosion when using Explicit State Space Exploration to verify protocols. We show experimentally that protocols exhibit transition locality. We present a verification algorithm that exploits transition locality as well as an implementation of it within the Mur$\varphi$ verifier. Our algorithm is compatible with all Breadth First (BF) optimization techniques present in the Mur$\varphi$ verifier and it is by no means a substitute for any of them. In fact, since our algorithm trades space with time, it is typically most useful when one runs out of memory and has already used all other state reduction techniques present in the Mur$\varphi$ verifier. Our experimental results show that using our approach we can typically save more than 40% of RAM with an average time penalty of about 50% when using (Mur$\varphi$) bit compression and 100% when using bit compression and hash compaction.
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Federico Mari, Igor Melatti, Ivano Salvo, and Enrico Tronci. "Undecidability of Quantized State Feedback Control for Discrete Time Linear Hybrid Systems." In Theoretical Aspects of Computing – ICTAC 2012, edited by A. Roychoudhury and M. D'Souza, 243–258. Lecture Notes in Computer Science 7521. Springer Berlin Heidelberg, 2012. ISBN: 978-3-642-32942-5. DOI: 10.1007/978-3-642-32943-2_19.
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