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Author (down) Fischer, S.; Ehrig, R.; Schaefer, S.; Tronci, E.; Mancini, T.; Egli, M.; Ille, F.; Krueger, T.H.C.; Leeners, B.; Roeblitz, S.
Title Mathematical Modeling and Simulation Provides Evidence for New Strategies of Ovarian Stimulation Type Journal Article
Year 2021 Publication Frontiers in Endocrinology Abbreviated Journal
Volume 12 Issue Pages 117
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Abstract New approaches to ovarian stimulation protocols, such as luteal start, random start or double stimulation, allow for flexibility in ovarian stimulation at different phases of the menstrual cycle. It has been proposed that the success of these methods is based on the continuous growth of multiple cohorts (“waves”) of follicles throughout the menstrual cycle which leads to the availability of ovarian follicles for ovarian controlled stimulation at several time points. Though several preliminary studies have been published, their scientific evidence has not been considered as being strong enough to integrate these results into routine clinical practice. This work aims at adding further scientific evidence about the efficiency of variable-start protocols and underpinning the theory of follicular waves by using mathematical modeling and numerical simulations. For this purpose, we have modified and coupled two previously published models, one describing the time course of hormones and one describing competitive follicular growth in a normal menstrual cycle. The coupled model is used to test ovarian stimulation protocols in silico. Simulation results show the occurrence of follicles in a wave-like manner during a normal menstrual cycle and qualitatively predict the outcome of ovarian stimulation initiated at different time points of the menstrual cycle.
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1664-2392 ISBN Medium
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Notes Approved no
Call Number MCLab @ davi @ ref10.3389/fendo.2021.613048 Serial 189
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Author (down) Fantechi, Alessandro; Gnesi, Stefania; Mazzanti, Franco; Pugliese, Rosario; Tronci, Enrico
Title A Symbolic Model Checker for ACTL Type Conference Article
Year 1998 Publication International Workshop on Current Trends in Applied Formal Method (FM-Trends) Abbreviated Journal
Volume Issue Pages 228-242
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Abstract We present SAM, a symbolic model checker for ACTL, the action-based version of CTL. SAM relies on implicit representations of Labeled Transition Systems (LTSs), the semantic domain for ACTL formulae, and uses symbolic manipulation algorithms. SAM has been realized by translating (networks of) LTSs and, possibly recursive, ACTL formulae into BSP (Boolean Symbolic Programming), a programming language aiming at defining computations on boolean functions, and by using the BSP interpreter to carry out computations (i.e. verifications).
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Publisher Springer Place of Publication Boppard, Germany Editor Hutter, D.; Stephan, W.; Traverso, P.; Ullmann, M.
Language Summary Language Original Title
Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title
Series Volume 1641 Series Issue Edition
ISSN 3-540-66462-9 ISBN Medium
Area Expedition Conference
Notes Approved yes
Call Number Sapienza @ mari @ fm-trends98 Serial 51
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Author (down) Ehrig, R.; Dierkes, T.; Schaefer, S.; Roeblitz, S.; Tronci, E.; Mancini, T.; Salvo, I.; Alimguzhin, V.; Mari, F.; Melatti, I.; Massini, A.; Leeners, B.; Krueger, T.H.C.; Egli, M.; Ille, F.
Title An integrative approach for model driven computation of treatments in reproductive medicine Type Conference Article
Year 2015 Publication Proceedings of the 15th International Symposium on Mathematical and Computational Biology (BIOMAT 2015), Rorkee, India Abbreviated Journal
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Notes Approved no
Call Number Sapienza @ preissler @ Ehrig_etal2015 Serial 144
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Author (down) Driouich, Y.; Parente, M.; Tronci, E.
Title Modeling cyber-physical systems for automatic verification Type Conference Article
Year 2017 Publication 14th International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design (SMACD 2017) Abbreviated Journal
Volume Issue Pages 1-4
Keywords cyber-physical systems;formal verification;maximum power point trackers;power engineering computing;Modelica;automatic verification;complex power electronics systems;cyber-physical systems modeling;distributed maximum power point tracking system;open standard modeling language;Computational modeling;Control systems;Integrated circuit modeling;Mathematical model;Maximum power point trackers;Object oriented modeling;Radiation effects;Automatic Formal Verification;Cyber-Physical Systems;DMPPT;Modeling;Photovoltaic systems;Simulation;System Analysis and Design
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Notes Approved no
Call Number MCLab @ davi @ ref7981621 Serial 168
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Author (down) Driouich, Y.; Parente, M.; Tronci, E.
Title A methodology for a complete simulation of Cyber-Physical Energy Systems Type Conference Article
Year 2018 Publication EESMS 2018 – Environmental, Energy, and Structural Monitoring Systems, Proceedings Abbreviated Journal
Volume Issue Pages 1-5
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Publisher Place of Publication Editor
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Notes Approved no
Call Number MCLab @ davi @ Driouich20181 Serial 169
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Author (down) Driouich, Y.; Parente, M.; Tronci, E.
Title Model Checking Cyber-Physical Energy Systems Type Conference Article
Year 2018 Publication Proceedings of 2017 International Renewable and Sustainable Energy Conference, IRSEC 2017 Abbreviated Journal
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Publisher Institute of Electrical and Electronics Engineers Inc. Place of Publication Editor
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Notes Approved no
Call Number MCLab @ davi @ Driouich2018 Serial 177
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Author (down) Dipoppa, G.; D'Alessandro, G.; Semprini, R.; Tronci, E.
Title Integrating Automatic Verification of Safety Requirements in Railway Interlocking System Design Type Conference Article
Year 2001 Publication High Assurance Systems Engineering, 2001. Sixth IEEE International Symposium on Abbreviated Journal
Volume Issue Pages 209-219
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Abstract A railway interlocking system (RIS) is an embedded system (namely a supervisory control system) that ensures the safe, operation of the devices in a railway station. RIS is a safety critical system. We explore the possibility of integrating automatic formal verification methods in a given industry RIS design flow. The main obstructions to be overcome in our work are: selecting a formal verification tool that is efficient enough to solve the verification problems at hand; and devising a cost effective integration strategy for such tool. We were able to devise a successful integration strategy meeting the above constraints without requiring major modification in the pre-existent design flow nor retraining of personnel. We run verification experiments for a RIS designed for the Singapore Subway. The experiments show that the RIS design flow obtained from our integration strategy is able to automatically verify real life RIS designs.
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Publisher IEEE Computer Society Place of Publication Albuquerque, NM, USA Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0-7695-1275-5 ISBN Medium
Area Expedition Conference
Notes Approved yes
Call Number Sapienza @ mari @ hase01 Serial 45
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Author (down) Della Penna, Giuseppe; Tofani, Alberto; Pecorari, Marcello; Raparelli, Orazio; Intrigila, Benedetto; Melatti, Igor; Tronci, Enrico
Title A Case Study on Automated Generation of Integration Tests Type Conference Article
Year 2006 Publication Fdl Abbreviated Journal
Volume Issue Pages 278-284
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Publisher Ecsi Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 978-3-00-019710-9 ISBN Medium
Area Expedition Conference
Notes Approved yes
Call Number Sapienza @ mari @ Dtprimt06 Serial 27
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Author (down) Della Penna, Giuseppe; Magazzeni, Daniele; Tofani, Alberto; Intrigila, Benedetto; Melatti, Igor; Tronci, Enrico
Title Automated Generation Of Optimal Controllers Through Model Checking Techniques Type Book Chapter
Year 2008 Publication Informatics in Control Automation and Robotics. Selected Papers from ICINCO 2006 Abbreviated Journal
Volume Issue Pages 107-119
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Publisher Springer Place of Publication Editor
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Notes Approved yes
Call Number Sapienza @ mari @ Dmtmt08 Serial 26
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Author (down) Della Penna, Giuseppe; Magazzeni, Daniele; Tofani, Alberto; Intrigila, Benedetto; Melatti, Igor; Tronci, Enrico
Title Automated Generation of Optimal Controllers through Model Checking Techniques Type Conference Article
Year 2006 Publication Icinco-Icso Abbreviated Journal
Volume Issue Pages 26-33
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Abstract We present a methodology for the synthesis of controllers, which exploits (explicit) model checking techniques. That is, we can cope with the systematic exploration of a very large state space. This methodology can be applied to systems where other approaches fail. In particular, we can consider systems with an highly non-linear dynamics and lacking a uniform mathematical description (model). We can also consider situations where the required control action cannot be specified as a local action, and rather a kind of planning is required. Our methodology individuates first a raw optimal controller, then extends it to obtain a more robust one. A case study is presented which considers the well known truck-trailer obstacle avoidance parking problem, in a parking lot with obstacles on it. The complex non-linear dynamics of the truck-trailer system, within the presence of obstacles, makes the parking problem extremely hard. We show how, by our methodology, we can obtain optimal controllers with different degrees of robustness.
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Publisher INSTICC Press Place of Publication Editor Andrade-Cetto, J.; Ferrier, J.-L.; Pereira, J. M. C. D.; Filipe, J.
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 972-8865-59-7 ISBN Medium
Area Expedition Conference
Notes Approved yes
Call Number Sapienza @ mari @ Dimmtt06 Serial 79
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