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Mancini, T.; Mari, F.; Massini, A.; Melatti, I.; Tronci, E. |
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Title |
Anytime system level verification via parallel random exhaustive hardware in the loop simulation |
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Journal Article |
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2016 |
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Microprocessors and Microsystems |
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41 |
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12-28 |
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Model Checking of Hybrid Systems; Model checking driven simulation; Hardware in the loop simulation |
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Abstract System level verification of cyber-physical systems has the goal of verifying that the whole (i.e., software + hardware) system meets the given specifications. Model checkers for hybrid systems cannot handle system level verification of actual systems. Thus, Hardware In the Loop Simulation (HILS) is currently the main workhorse for system level verification. By using model checking driven exhaustive HILS, System Level Formal Verification (SLFV) can be effectively carried out for actual systems. We present a parallel random exhaustive HILS based model checker for hybrid systems that, by simulating all operational scenarios exactly once in a uniform random order, is able to provide, at any time during the verification process, an upper bound to the probability that the System Under Verification exhibits an error in a yet-to-be-simulated scenario (Omission Probability). We show effectiveness of the proposed approach by presenting experimental results on SLFV of the Inverted Pendulum on a Cart and the Fuel Control System examples in the Simulink distribution. To the best of our knowledge, no previously published model checker can exhaustively verify hybrid systems of such a size and provide at any time an upper bound to the Omission Probability. |
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0141-9331 |
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MCLab @ davi @ Mancini201612 |
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155 |
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Della Penna, Giuseppe; Intrigila, Benedetto; Tronci, Enrico; Venturini Zilli, Marisa |
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Title |
Synchronized regular expressions |
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2003 |
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Acta Inf. |
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39 |
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1 |
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31-70 |
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Text manipulation is one of the most common tasks for everyone using a computer. The increasing number of textual information in electronic format that every computer user collects everyday also increases the need of more powerful tools to interact with texts. Indeed, much work has been done to provide simple and versatile tools that can be useful for the most common text manipulation tasks. Regular Expressions (RE), introduced by Kleene, are well known in the formal language theory. RE have been extended in various ways, depending on the application of interest. In almost all the implementations of RE search algorithms (e.g. the egrep [15] UNIX command, or the Perl [20] language pattern matching constructs) we find backreferences, i.e. expressions that make reference to the string matched by a previous subexpression. Generally speaking, it seems that all kinds of synchronizations between subexpressions in a RE can be very useful when interacting with texts. In this paper we introduce the Synchronized Regular Expressions (SRE) as an extension of the Regular Expressions. We use SRE to present a formal study of the already known backreferences extension, and of a new extension proposed by us, which we call the synchronized exponents. Moreover, since we are dealing with formalisms that should have a practical utility and be used in real applications, we have the problem of how to present SRE to the final users. Therefore, in this paper we also propose a user-friendly syntax for SRE to be used in implementations of SRE-powered search algorithms. |
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yes |
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Sapienza @ mari @ actainf03 |
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39 |
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Maggioli, F.; Mancini, T.; Tronci, E. |
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SBML2Modelica: Integrating biochemical models within open-standard simulation ecosystems |
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Journal Article |
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2019 |
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Bioinformatics |
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36 |
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7 |
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2165–2172 |
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SBML is the most widespread language for the definition of biochemical models. Although dozens of SBML simulators are available, there is a general lack of support to the integration of SBML models within open-standard general-purpose simulation ecosystems. This hinders co-simulation and integration of SBML models within larger model networks, in order to, e.g., enable in-silico clinical trials of drugs, pharmacological protocols, or engineering artefacts such as biomedical devices against Virtual Physiological Human models.Modelica is one of the most popular existing open-standard general-purpose simulation languages, supported by many simulators. Modelica models are especially suited for the definition of complex networks of heterogeneous models from virtually all application domains. Models written in Modelica (and in 100+ other languages) can be readily exported into black-box Functional Mock-Up Units (FMUs), and seamlessly co-simulated and integrated into larger model networks within open-standard language-independent simulation ecosystems.In order to enable SBML model integration within heterogeneous model networks, we present SBML2Modelica, a software system translating SBML models into well-structured, user-intelligible, easily modifiable Modelica models. SBML2Modelica is SBML Level 3 Version 2 -compliant and succeeds on 96.47% of the SBML Test Suite Core (with a few rare, intricate, and easily avoidable combinations of constructs unsupported and cleanly signalled to the user). Our experimental campaign on 613 models from the BioModels database (with up to 5438 variables) shows that the major open-source (general-purpose) Modelica and FMU simulators achieve performance comparable to state-of-the-art specialised SBML simulators.SBML2Modelica is written in Java and is freely available for non-commercial use at https://bitbucket.org/mclab/sbml2modelica |
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1367-4803 |
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MCLab @ davi @ ref10.1093/bioinformatics/btz860 |
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179 |
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Mancini, T.; Massini, A.; Tronci, E. |
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Title |
Parallelization of Cycle-Based Logic Simulation |
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2017 |
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Parallel Processing Letters |
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27 |
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02 |
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MCLab @ davi @ |
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166 |
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Cesta, Amedeo; Finzi, Alberto; Fratini, Simone; Orlandini, Andrea; Tronci, Enrico |
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Title |
Validation and verification issues in a timeline-based planning system |
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Journal Article |
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2010 |
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The Knowledge Engineering Review |
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25 |
Issue |
03 |
Pages |
299-318 |
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One of the key points to take into account to foster effective introduction of AI planning and scheduling systems in real world is to develop end user trust in the related technologies. Automated planning and scheduling systems often brings solutions to the users which are neither “obvious†nor immediately acceptable for them. This is due to the ability of these tools to take into account quite an amount of temporal and causal constraints and to employ resolution processes often designed to optimize the solution with respect to non trivial evaluation functions. To increase technology trust, the study of tools for verifying and validating plans and schedules produced by AI systems might be instrumental. In general, validation and verification techniques represent a needed complementary technology in developing domain independent architectures for automated problem solving. This paper presents a preliminary report of the issues concerned with the use of two software tools for formal verification of finite state systems to the validation of the solutions produced by MrSPOCK, a recent effort for building a timeline based planning tool in an ESA project. |
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Cambridge University Press |
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yes |
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Sapienza @ mari @ Cffot10 |
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18 |
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Mari, Federico; Melatti, Igor; Salvo, Ivano; Tronci, Enrico |
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Model Based Synthesis of Control Software from System Level Formal Specifications |
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2014 |
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ACM TRANSACTIONS ON SOFTWARE ENGINEERING AND METHODOLOGY |
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ACM TRANSACTIONS ON SOFTWARE ENGINEERING AND METHODOLOGY |
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23 |
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1 |
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Article 6 |
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ACM |
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1049-331X |
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Sapienza @ melatti @ |
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110 |
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Della Penna, Giuseppe; Intrigila, Benedetto; Magazzeni, Daniele; Melatti, Igor; Tronci, Enrico |
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CGMurphi: Automatic synthesis of numerical controllers for nonlinear hybrid systems |
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2013 |
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European Journal of Control |
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European Journal of Control |
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19 |
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1 |
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14-36 |
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Elsevier North-Holland, Inc. |
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0947-3580 |
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Sapienza @ melatti @ |
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114 |
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Bobbio, Andrea; Ciancamerla, Ester; Minichino, Michele; Tronci, Enrico |
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Functional analysis of a telecontrol system and stochastic measures of its GSM/GPRS connections |
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2005 |
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Archives of Transport – International Journal of Transport Problems |
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17 |
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3-4 |
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yes |
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Sapienza @ mari @ jtp05 |
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31 |
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Bucciarelli, Antonio; Piperno, Adolfo; Salvo, Ivano |
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Intersection types and λ-definability |
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2003 |
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Mathematical Structures in Computer Science |
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13 |
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1 |
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15-53 |
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This paper presents a novel method for comparing computational properties of λ-terms that are typeable with intersection types, with respect to terms that are typeable with Curry types. We introduce a translation from intersection typing derivations to Curry typeable terms that is preserved by β-reduction: this allows the simulation of a computation starting from a term typeable in the intersection discipline by means of a computation starting from a simply typeable term. Our approach proves strong normalisation for the intersection system naturally by means of purely syntactical techniques. The paper extends the results presented in Bucciarelli et al. (1999) to the whole intersection type system of Barendregt, Coppo and Dezani, thus providing a complete proof of the conjecture, proposed in Leivant (1990), that all functions uniformly definable using intersection types are already definable using Curry types. |
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Cambridge University Press |
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New York, NY, USA |
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0960-1295 |
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Sapienza @ mari @ Bucciarelli-Piperno-Salvo:MSCS-03 |
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69 |
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Fischer, S.; Ehrig, R.; Schaefer, S.; Tronci, E.; Mancini, T.; Egli, M.; Ille, F.; Krueger, T.H.C.; Leeners, B.; Roeblitz, S. |
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Title |
Mathematical Modeling and Simulation Provides Evidence for New Strategies of Ovarian Stimulation |
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2021 |
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Frontiers in Endocrinology |
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12 |
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117 |
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New approaches to ovarian stimulation protocols, such as luteal start, random start or double stimulation, allow for flexibility in ovarian stimulation at different phases of the menstrual cycle. It has been proposed that the success of these methods is based on the continuous growth of multiple cohorts (“waves”) of follicles throughout the menstrual cycle which leads to the availability of ovarian follicles for ovarian controlled stimulation at several time points. Though several preliminary studies have been published, their scientific evidence has not been considered as being strong enough to integrate these results into routine clinical practice. This work aims at adding further scientific evidence about the efficiency of variable-start protocols and underpinning the theory of follicular waves by using mathematical modeling and numerical simulations. For this purpose, we have modified and coupled two previously published models, one describing the time course of hormones and one describing competitive follicular growth in a normal menstrual cycle. The coupled model is used to test ovarian stimulation protocols in silico. Simulation results show the occurrence of follicles in a wave-like manner during a normal menstrual cycle and qualitatively predict the outcome of ovarian stimulation initiated at different time points of the menstrual cycle. |
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1664-2392 |
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MCLab @ davi @ ref10.3389/fendo.2021.613048 |
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189 |
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