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Author Mancini, T.; Mari, F.; Massini, A.; Melatti, I.; Tronci, E. pdf  url
doi  openurl
  Title Anytime system level verification via parallel random exhaustive hardware in the loop simulation Type (up) Journal Article
  Year 2016 Publication Microprocessors and Microsystems Abbreviated Journal  
  Volume 41 Issue Pages 12-28  
  Keywords Model Checking of Hybrid Systems; Model checking driven simulation; Hardware in the loop simulation  
  Abstract Abstract System level verification of cyber-physical systems has the goal of verifying that the whole (i.e., software + hardware) system meets the given specifications. Model checkers for hybrid systems cannot handle system level verification of actual systems. Thus, Hardware In the Loop Simulation (HILS) is currently the main workhorse for system level verification. By using model checking driven exhaustive HILS, System Level Formal Verification (SLFV) can be effectively carried out for actual systems. We present a parallel random exhaustive HILS based model checker for hybrid systems that, by simulating all operational scenarios exactly once in a uniform random order, is able to provide, at any time during the verification process, an upper bound to the probability that the System Under Verification exhibits an error in a yet-to-be-simulated scenario (Omission Probability). We show effectiveness of the proposed approach by presenting experimental results on SLFV of the Inverted Pendulum on a Cart and the Fuel Control System examples in the Simulink distribution. To the best of our knowledge, no previously published model checker can exhaustively verify hybrid systems of such a size and provide at any time an upper bound to the Omission Probability.  
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  ISSN 0141-9331 ISBN Medium  
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  Notes Approved no  
  Call Number MCLab @ davi @ Mancini201612 Serial 155  
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Author Leeners, B.; Kruger, T.H.C.; Geraedts, K.; Tronci, E.; Mancini, T.; Ille, F.; Egli, M.; Röblitz, S.; Saleh, L.; Spanaus, K.; Schippert, C.; Zhang, Y.; Hengartner, M.P. pdf  url
doi  openurl
  Title Lack of Associations between Female Hormone Levels and Visuospatial Working Memory, Divided Attention and Cognitive Bias across Two Consecutive Menstrual Cycles Type (up) Journal Article
  Year 2017 Publication Frontiers in Behavioral Neuroscience Abbreviated Journal  
  Volume 11 Issue Pages 120  
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  Abstract Background: Interpretation of observational studies on associations between prefrontal cognitive functioning and hormone levels across the female menstrual cycle is complicated due to small sample sizes and poor replicability. Methods: This observational multisite study comprised data of n=88 menstruating women from Hannover, Germany, and Zurich, Switzerland, assessed during a first cycle and n=68 re-assessed during a second cycle to rule out practice effects and false-positive chance findings. We assessed visuospatial working memory, attention, cognitive bias and hormone levels at four consecutive time-points across both cycles. In addition to inter-individual differences we examined intra-individual change over time (i.e., within-subject effects). Results: Oestrogen, progesterone and testosterone did not relate to inter-individual differences in cognitive functioning. There was a significant negative association between intra-individual change in progesterone and change in working memory from pre-ovulatory to mid-luteal phase during the first cycle, but that association did not replicate in the second cycle. Intra-individual change in testosterone related negatively to change in cognitive bias from menstrual to pre-ovulatory as well as from pre-ovulatory to mid-luteal phase in the first cycle, but these associations did not replicate in the second cycle. Conclusions: There is no consistent association between women's hormone levels, in particular oestrogen and progesterone, and attention, working memory and cognitive bias. That is, anecdotal findings observed during the first cycle did not replicate in the second cycle, suggesting that these are false-positives attributable to random variation and systematic biases such as practice effects. Due to methodological limitations, positive findings in the published literature must be interpreted with reservation.  
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  ISSN 1662-5153 ISBN Medium  
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  Notes Approved no  
  Call Number Sapienza @ mari @ ref10.3389/fnbeh.2017.00120 Serial 167  
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Author Mancini, T. ; Mari, F.; Massini, A.; Melatti, I.; Salvo, I.; Tronci, E. pdf  doi
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  Title On minimising the maximum expected verification time Type (up) Journal Article
  Year 2017 Publication Information Processing Letters Abbreviated Journal  
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  Call Number Sapienza @ mari @ Serial 163  
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Author Hengartner, M. P.; Kruger, T. H. C.; Geraedts, K.; Tronci, E.; Mancini, T.; Ille, F.; Egli, M.; Röblitz, S.; Ehrig, R.; Saleh, L.; Spanaus, K.; Schippert, C.; Zhang, Y.; Leeners, B. pdf  doi
openurl 
  Title Negative affect is unrelated to fluctuations in hormone levels across the menstrual cycle: Evidence from a multisite observational study across two successive cycles Type (up) Journal Article
  Year 2017 Publication Journal of Psychosomatic Research Abbreviated Journal  
  Volume 99 Issue Pages 21-27  
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  Call Number MCLab @ davi @ Serial 165  
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Author Mancini, T.; Massini, A.; Tronci, E. pdf  doi
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  Title Parallelization of Cycle-Based Logic Simulation Type (up) Journal Article
  Year 2017 Publication Parallel Processing Letters Abbreviated Journal  
  Volume 27 Issue 02 Pages  
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  Call Number MCLab @ davi @ Serial 166  
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Author Maggioli, F.; Mancini, T.; Tronci, E. pdf  url
doi  openurl
  Title SBML2Modelica: Integrating biochemical models within open-standard simulation ecosystems Type (up) Journal Article
  Year 2019 Publication Bioinformatics Abbreviated Journal  
  Volume 36 Issue 7 Pages 2165–2172  
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  Abstract SBML is the most widespread language for the definition of biochemical models. Although dozens of SBML simulators are available, there is a general lack of support to the integration of SBML models within open-standard general-purpose simulation ecosystems. This hinders co-simulation and integration of SBML models within larger model networks, in order to, e.g., enable in-silico clinical trials of drugs, pharmacological protocols, or engineering artefacts such as biomedical devices against Virtual Physiological Human models.Modelica is one of the most popular existing open-standard general-purpose simulation languages, supported by many simulators. Modelica models are especially suited for the definition of complex networks of heterogeneous models from virtually all application domains. Models written in Modelica (and in 100+ other languages) can be readily exported into black-box Functional Mock-Up Units (FMUs), and seamlessly co-simulated and integrated into larger model networks within open-standard language-independent simulation ecosystems.In order to enable SBML model integration within heterogeneous model networks, we present SBML2Modelica, a software system translating SBML models into well-structured, user-intelligible, easily modifiable Modelica models. SBML2Modelica is SBML Level 3 Version 2 -compliant and succeeds on 96.47% of the SBML Test Suite Core (with a few rare, intricate, and easily avoidable combinations of constructs unsupported and cleanly signalled to the user). Our experimental campaign on 613 models from the BioModels database (with up to 5438 variables) shows that the major open-source (general-purpose) Modelica and FMU simulators achieve performance comparable to state-of-the-art specialised SBML simulators.SBML2Modelica is written in Java and is freely available for non-commercial use at https://bitbucket.org/mclab/sbml2modelica  
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  ISSN 1367-4803 ISBN Medium  
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  Notes Approved no  
  Call Number MCLab @ davi @ ref10.1093/bioinformatics/btz860 Serial 179  
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Author Hayes, B. P. ; Melatti, I.; Mancini, T.; Prodanovic, M.; Tronci, E. pdf  url
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  Title Residential Demand Management using Individualised Demand Aware Price Policies Type (up) Journal Article
  Year 2017 Publication IEEE Transactions On Smart Grid Abbreviated Journal  
  Volume 8 Issue 3 Pages 1284-1294  
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  Call Number MCLab @ davi @ Serial 157  
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Author Mancini, T.; Mari, F.; Massini, A.; Melatti, I.; Tronci, E. pdf  doi
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  Title SyLVaaS: System Level Formal Verification as a Service Type (up) Journal Article
  Year 2016 Publication Fundamenta Informaticae Abbreviated Journal  
  Volume 149 Issue 1-2 Pages 101-132  
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  Call Number MCLab @ davi @ DBLP:journals/fuin/ManciniMMMT16 Serial 160  
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Author Leeners, B.; Krueger, T.H.C.; Geraedts, K.; Tronci, E.; Mancini, T.; Egli, M.; Roeblitz, S.; Saleh, L.; Spanaus, K.; Schippert, C.; Zhang, Y.; Ille, F. pdf  url
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  Title Associations Between Natural Physiological and Supraphysiological Estradiol Levels and Stress Perception Type (up) Journal Article
  Year 2019 Publication Frontiers in Psychology Abbreviated Journal  
  Volume 10 Issue Pages 1296  
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  Abstract Stress is a risk factor for impaired general, mental and reproductive health. The role of physiological and supraphysiological estradiol concentrations in stress perception and stress processing is less well understood. We therefore, conducted a prospective observational study to investigate the association between estradiol, stress perception and stress-related cognitive performance within serial measurements either during the natural menstrual cycle or during fertility treatment, where estradiol levels are strongly above the physiological level of a natural cycle and consequently, represent a good model to study dose-dependent effects of estradiol. Data from 44 women receiving in vitro fertilization at the Department of Reproductive Endocrinology in Zurich, Switzerland was compared to data from 88 women with measurements during their natural menstrual cycle. The german version of the Perceived Stress Questionnaire (PSQ) and the Cognitive Bias Test (CBT), in which cognitive performance is tested under time stress were used to evaluate subjective and functional aspects of stress. Estradiol levels were investigated at four different time points during the menstrual cycle and at two different time points during a fertility treatment. Cycle phase were associated with PSQ worry and cognitive bias in normally cycling women, but different phases of fertility treatment were not associated with subjectively perceived stress and stress-related cognitive bias. PSQ lack of joy and PSQ demands related to CBT in women receiving fertility treatment but not in women with a normal menstrual cycle. Only strong changes of the estradiol level during fertility treatment were weakly associated with CBT, but not with subjectively experienced stress. Our research emphasises the multidimensional character of stress and the necessity to adjust stress research to the complex nature of stress perception and processing. Infertility is associated with an increased psychological burden in patients. However, not all phases of the process to overcome infertility do significantly increase patient stress levels. Also, research on the psychological burden of infertility should consider that stress may vary during the different phases of fertility treatment.  
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  ISSN 1664-1078 ISBN Medium  
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  Call Number MCLab @ davi @ ref10.3389/fpsyg.2019.01296 Serial 178  
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Author Tortora, L.; Meynen, G.; Bijlsma, J.; Tronci, E.; Ferracuti, S. pdf  url
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  Title Neuroprediction and A.I. in Forensic Psychiatry and Criminal Justice: A Neurolaw Perspective Type (up) Journal Article
  Year 2020 Publication Frontiers in Psychology Abbreviated Journal  
  Volume 11 Issue Pages 220  
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  Abstract Advances in the use of neuroimaging in combination with A.I., and specifically the use of machine learning techniques, have led to the development of brain-reading technologies which, in the nearby future, could have many applications, such as lie detection, neuromarketing or brain-computer interfaces. Some of these could, in principle, also be used in forensic psychiatry. The application of these methods in forensic psychiatry could, for instance, be helpful to increase the accuracy of risk assessment and to identify possible interventions. This technique could be referred to as ‘A.I. neuroprediction,Â’ and involves identifying potential neurocognitive markers for the prediction of recidivism. However, the future implications of this technique and the role of neuroscience and A.I. in violence risk assessment remain to be established. In this paper, we review and analyze the literature concerning the use of brain-reading A.I. for neuroprediction of violence and rearrest to identify possibilities and challenges in the future use of these techniques in the fields of forensic psychiatry and criminal justice, considering legal implications and ethical issues. The analysis suggests that additional research is required on A.I. neuroprediction techniques, and there is still a great need to understand how they can be implemented in risk assessment in the field of forensic psychiatry. Besides the alluring potential of A.I. neuroprediction, we argue that its use in criminal justice and forensic psychiatry should be subjected to thorough harms/benefits analyses not only when these technologies will be fully available, but also while they are being researched and developed.  
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  ISSN 1664-1078 ISBN Medium  
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  Notes Approved no  
  Call Number MCLab @ davi @ Neuroprediction-2020 Serial 180  
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